AKT-1/2
Catalog Number: E10840
Two serine/threonine kinases, designated AKT-1 and AKT-2 (alternatively referred to as PKB or RacPK), exhibit sequence homology with the protein kinase A and C families and are encoded by the c-akt proto-oncogene. AKT-1 and AKT-2 contain a Pleckstrin homology (PH) domain and are activated by PDGF stimulation. This activation is dependent on PDGFR-beta tyrosine residues 740 and 751, which bind the 85kDa subunit of the phosphatidylinositol 3-kinase (PI-3 kinase) complex. The protein may signal downstream of the PI kinases.
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Product Details
| Catalog Number | E10840 |
| Host | Rabbit |
| Clone Name | na |
| Dilution | 1:50 |
| Application | IHC-P, WB |
| Species Reactivity | Hu, Ms, Rt |
| Quantity | 0.1ml |
| Regulatory Rating | Research Use Only |
| Entrez | 207 Akt1 / 208 Akt2 |
| Storage Requirement | 2-8°C |
| Isotype | Rabbit IgG |
| Immunogen | A synthetic peptide from N-terminus of human AKT-1. |
| Target MW | 60 kDa(Akt1) & 56 kDa (Akt2) |
| Formulation | 0.1 ml immunogen affinity purified immunoglobulin from rabbit serum in 10mM PBS/1% BSA buffer pH 7.4 with 0.1% sodium azide. |
| Price | $95.00 |
