CD150
Catalog Number: E13944
CD150, a novel glycoprotein of 70kDa, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells.
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Product Details
| Catalog Number | E13944 |
| Host | Rabbit |
| Clone Name | na |
| Dilution | na |
| Application | WB |
| Species Reactivity | Hu |
| Quantity | 1ml |
| Regulatory Rating | Research Use Only |
| Entrez | 6504 |
| Storage Requirement | 2-8°C |
| Isotype | Rabbit IgG |
| Immunogen | Recombinant protein encoding aa 1-136 of human CD150. |
| Target MW | 37 kDa |
| Formulation | 1 ml affinity purified rabbit polyclonal antibody at 0.2mg/ml in 10mM PBS, pH 7.4 with BSA and sodium azide. |
| Price | $379.00 |
