Welcome Guest

PRODUCT DETAILS



Feel free to post
comments and
questions to us on
spring.orders@ventana.roche.com

or call us direct at
(925) 474.8440

PD-L1/CD274 (SP142)

< Back
up arrow
Human placenta stained with anti-PD-L1 antibody
Human tonsil stained with anti-PD-L1 antibody
Human lung squamous cell carcinoma stained with anti-PD-L1 antibody
Human Hodgkin's lymphoma stained with anti-PD-L1 antibody
Human cervical squamous cell carcinoma stained with anti-PD-L1 antibody
Human pancreatic adenocarcinoma stained with anti-PD-L1 antibody
Human prostate adenocarcinoma stained with anti-PD-L1 antibody
Human skin squamous cell carcinoma stained with anti-PD-L1 antibody
down arrow
Human placenta stained with anti-PD-L1 antibody

Human placenta stained with anti-PD-L1 antibody

QuantityCatalog No.VolumeDilutionPrice
M44200.1ml100$380.00
M44220.5ml100$1,900.00
M44241.0ml100$3,800.00
M442S25ul100$99.00
M44217.0ml $500.00

Programmed cell death ligand 1 (PD-L1) also known as cluster of differentiation (CD274) or B7 homolog 1 (B7-H1) is a type 1 transmembrane protein involved in the regulation of cellular and humoral immune responses. The interaction of PD-L1 with its receptor PD-1 provides both stimulatory and inhibitory signals in regulating T cell activation and tolerance during pregnancy,tissue allografts, autoimmune disease and malignant transformation. PD-L1 is mainly expressed in antigen presenting cells, activated T and B cells, placenta, and some tumors such as melanoma, diffuse large B-cell lymphoma, and carcinoma of the lung, colon, and rectum.

Product Specification Sheets:

M442(PD-L1)_RUO_A.pdf

Material Safety Data Sheets:

US: Primary Abs_sb047_2.0.pdf

INTL/EU: Primary abs_sb047EU_2.0.pdf

Product Details:

  • TechnologyRabbit Monoclonal
  • Clone NameSP142
  • ApplicationIHC-P
  • Species Reactivity
  •   TestedHu
  •   Predicted by homologyN/A
  • IsotypeRabbit IgG
  • ImmunogenSynthetic peptide derived from the C-terminus of human PD-L1 protein.
  • Cellular LocalizationMembrane
  • Control TissuePlacenta
  • Regulatory RatingResearch Use Only (RUO)
  • Entrez29126
  • Storage Requirement2-8°C
  • Target Molecular Weight32 kDa
  • FormulationRefer to Data Sheet