Western Blot analysis of Calu3 cell lysate
Human renal cell carcinoma stained with anti-Fn14 antibody
Fn14/Tweak receptor/CD266/TNFRSF12A, tumor necrosis factor receptor superfamily member 12A, is the receptor for Tweak, a member of the TNF family and was first described as a weak inducer of apoptosis in some cell types. It is thought to promote angiogenesis and the proliferation of endothelial cells as well as modulating cellular adhesion to matrix proteins.
